Applied biopharmaceutics & pharmacokinetics / Applied biopharmaceutics and pharmacokinetics editors, Leon Shargel, Andrew B.C. Yu. - Seventh edition. - xvii, 910 pages : illustrations ; 24 cm

Includes bibliographical references and index.

Introduction to biopharmaceutics and pharmacokinetics -- Mathematic fundamentals in pharmacokinetics -- Biostatistics -- One compartment open model : IV bolus injection -- Multicompartmental models : IV bolus injection -- Intravenous infusion -- Drug elimination and clearance -- Pharmacokinetics of oral absorption -- Multiple dosage regimens -- Nonlinear pharmacokinetics -- Physiologic drug distribution and protein binding -- Renal and hepatic elimination of drugs -- Pharmacogenetics and drug metabolism -- Physiologic factors related to drug absorption -- Biopharmaceutic considerations in drug product design -- Drug product performance, in vivo : bioavailability and bioequivalence -- Biopharmaceutic aspects of the active pharmaceutical ingredient and pharmaceutical equivalence -- Impact of biopharmaceutics on drug product quality and clinical efficacy -- Modified release drug products and drug devices -- Targeted drug delivery systems and biotechnology products -- Relationship between pharmacokinetic and pharmacodynamics -- Application of pharmacokinetics in clinical situations -- Application of pharmacokinetics in specific populations -- Dosage adjustment in renal and hepatic disease -- Empirical models, mechanistic models, statistical moment and noncompartmental analysis.

97898131500508 (Pbk. : NP)


Biopharmaceutics.
Pharmacokinetics.
Biopharmaceutics.
Pharmacokinetics.
Drug Administration Routes.
Models, Chemical.

RM301.4 / .A67 2016

615.7

QV 38