MARC details
| 000 -LEADER |
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| fixed length control field |
03043nam a22001817a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER |
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OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
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20220404141402.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
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220404b |||||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE |
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| Original cataloging agency |
MMSU |
| Language of cataloging |
ULS |
| Transcribing agency |
ULS |
| 100 ## - MAIN ENTRY--PERSONAL NAME |
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| Personal name |
Alberto, Ayra Daniele L., Idor, Czar Ianne L., Mangabat, Jamaica F., Vitin, Julius M. |
| 245 ## - TITLE STATEMENT |
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| Title |
Antioxidant Activity and Hepatoprotective Property of Breadnut Seed (Artocarpus Camansi Blanco) Extract Against Carbontetrachloride Induced Liver Damage in Albino Rats / |
| Statement of responsibility, etc. |
Ayra Daniele L. Alberto., Czar Ianne L. Idor., Jamaica F. Mangabat., Julius M. Vitin20 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. |
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| Date of publication, distribution, etc. |
2014 |
| 300 ## - PHYSICAL DESCRIPTION |
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| Extent |
ix, 76 leaves |
| Other physical details |
28 CM. |
| 500 ## - GENERAL NOTE |
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| General note |
Thesis (Bachelor of Science in Pharmacy) -- Mariano Marcos State University - College of Health Sciences, Batac City |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE |
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| Bibliography, etc. note |
Bibliography: leaves 41-42 |
| 520 ## - SUMMARY, ETC. |
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| Summary, etc. |
ABSTRACT |
| Expansion of summary note |
ALBERTO, ADL., IDOR, CIL., MANGABAT, JF., VITIN, JM. Mariano Marcos State University, College of Health Sciences, Department of Pharmacy, 2906 City of Batac, March 2014. Antioxidant Activity and Hepatoprotective Property of Breadnut Seed (Artocarpus Camansi Blanco) Extract Against Carbontetrachloride Induced Liver Damage in Albino Rats.<br/>Adviser: Ms. Angelica May A. dela Cruz<br/>This experimental study was conducted to investigate the antioxidant activity and hepatoprotective property of Breadnut seed (Artocarpus Camansi Blanco) Extract against carbon tetrachloride-induced liver damage in albino rats. Artocarpus camansi Blanco extract was air-dried for four days and oven-dried for two days at 40°C then milled. Plant extract was obtained by 72-hour maceration with ethanol as solvent and rotary evaporation methods. The antioxidant property of ethanolic extracts of breadnut seed was evaluated by DPPH assay and TPC (total phenolic content) by Folin-Ciocalteau method. DPPH (1, 1-diphenyl-2-picrylhydrazil) assay of ACBE showed 11.427% free radical inhibition at a dose of 200mcgl/ml. total phenolic content was determined by spectrophotometry using gallic acid as the standard. The obtained total polyphenols as GAE per milligram extract was 33.208 mcg. <br/>For the hepatoprotective activity, test animals were divided into 4 groups with 3 animals each. For 7 days, group 1 (positive control), received Silymarin (25mg/kg), group 2 (negative control), received PNSS (10ml/kg); group 3 (treated group), received ACBE (0.2g/kg, po). By administering Carbon tetrachloride, the destruction in the liver was observed. Through tail vein puncture of the blood, changes in levels of biochemical markers of hepatic damage like SGOT and SGPT with histopathologic examination of the liver were tested in all groups. Treatment with ACBE (320mcg/ml) showed minimal efficacy. ACBE and positive control Silymarin showed no significant difference. The significant differences in the treatments were analyzed by t-test between results. Ther is significant difference between Ascorbic acid and ACBE while the hepatoprotective activity between Silymarin and ACBE showed no significant difference. <br/> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
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| Source of classification or shelving scheme |
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| Koha item type |
Thesis/Dissertation |