The Salicylates Obtained From The Bark Of Weeping Willow (Salix Sepulcralis, Salicaceae) As A Stimulant / Glaizaline A. Agustin., Joanna Marie S. Bautista., Winnie G. Erorita

Thesis (Bachelor of Science in Pharmacy) -- Mariano Marcos State University - College of Health Sciences, Batac City

Bibliography: leaves 43-44

ABSTRACT AGUSTIN, GLAIZALINE A., BAUTISTA, JOANNA MARIE S., ERORITA, WINNIE G. Undergraduate Thesis. Mariano Marcos State University, College of Health Sciences, Department of Pharmacy, City of Batac 2906, Ilocos Norte, March 2010 THE SALICYLATES OBTAINED FROM THE BARK OF WEEPING WILLOW (Salix Sepulcralis, Salicaceae) AS A STIMULANT Adviser: Imelda B. Corpuz
This study was conducted to investigate the stimulant effect of the salicylates obtained from the bark of the Weeping Willow (Salix sepulcralis). It utilized the experimental method in the conduct of the study. Twenty-eight healthy male Swiss mice were divided into three groups. The mice were treated by an oral administration with four (4) different doses starting with an initial dose of 1mg/kg and the increasing doses starting with an initial dose of 1mg/kg and the increasing dose were computed using the 0.6 log intervals with a maximum of four log intervals. The treatments were, T1=Distilled; T2=Caffeine, T3=Salicylates obtained from the Weeping Willow Bark. The analysis of Variance (ANOVA) was used to determine if there is a significant difference between Caffeine and Salicylates obtained from Weeping Willow Bark. Similarly, this is utilized to determine which among the doses of salicylates is the most effective. The study came out with the following findings: first, the crude extract from the Weeping Willow (Salix sepulcralis) bark showed a positive result in the confirmatory test for salicylates; Second, the salicylates obtained from the Weeping Willow (Salix sepulcralis) bark posses stimulant activity in varying doses. The greater the dose, the greater the stimulant activity it has. Thus, it is comparable to the salicylates obtained from the Weeping Willow (Salix sepulcralis) bark, However, are not comparable with the negative control. Finally, based on the findings, the salicylates obtained from the Weeping Willow (Salix sepulcralis) bark serves as good stimulant promoting a more active and alert body reflexes.