TY  - BOOK
AU  - Antalan, Judy A. [and five others]
TI  - Antipyretic activity of Mungo (Phaseolus radiatus) seed extract 
PY  - 2004///
N1  - Thesis (Bachelor of Science in Pharmacy) -- Mariano Marcos State University - College of Health Sciences, Batac City; Bibliography:  leaf 25
N2  - ABSTRACT; ABSTRACT
Antalan, J.A., Caleja, M.R., Carlos, J.R., Eraña, B.A. Martinez, M.R., Raralio, J.N..;  Mariano Marcos State University, College of Health Sciences, Department of Pharmacy, Batac City 2906 Ilocos Norte, October 2004. ANTIPYRETIC ACTIVITY OF MUNGO (Phaselous Radaitus) SEED EXTRACT
THESIS ADVISER: MS. JANELYN P. VIADO
This study was conducted to determine the effectiveness of mungo (Phaselous Radaitus) seed extract as antipyretic agent. It also determined the effective dose that produces the highest decrease in body temperature of the fever-induced test animals of the phytochemical substances present in the extract. The reflux method of extraction was employed. Extract was subjected to phytochemical analysis for the presence of alkaloid, saponin glycosides, tannins, anthraquinones, flavonoids, fats, fixed oil, proteins and carbohydrates, cardenolides and bufadionolides. The effectectiveness of the seed as antipyretic agent was tested in 12 fever-induced guinea pigs using the computer dose of 125 mg/kg, 250 mg/kg  and 300 mg/kg per body weight. Body temperature was measured after 30 minutes and hourly for 3 consecutive hours. The procedure was done for the 2nd and 3rd administration of the seed extract. The statistical used in the analysis of data was ANOVA. Results revealed that mungo seed extract contains alkaloids, saponin glycosides, tannins, carbohydrates, proteins and fixed oils. Mungo seed extract was capable of exerting its antipyretic effect up to one hour following extract administration and that the lowest dose manifested the greatest effect in decreasing effect in decreasing the body temperature of the fever-induced test animal. 



ER  -