TY  - BOOK
AU  - Binarao, Celian Lilet I. [and three others]
TI  - Efficacy of Siamese rough bush (Streblus asper) bark extract against Trichophyton mentagrophtytes 
PY  - 2007///
N1  - Thesis (Bachelor of Science in Pharmacy) -- Mariano Marcos State University - College of Health Sciences, Batac City; Bibliography:  leaves 33-35
N2  - ABSTRACT; ABSTRACT 
Binarao, Celian Lilet L., Co, Kristine G., Pascual, Mary Anne Q., Rabanal, Suzette T. . Undergraduate thesis. Mariano Marcos State University, College of Health Sciences, Department of Pharmacy, Batac City 2906 Ilocos Norte, October 2007. EFFICACY OF SIAMESE ROUGH BUSH (Streblush Asper) BARK EXTRACT AGAINST Trichopython Mentagrophytes
70 pp 
Thesis Adviser: Ms. Kristian Gay Y. Dutdut 
The study investigated the efficacy of Siamese Rough Bush (streblush asper) bark extract against Trichopython mentagrophytes. It was conducted from August to September 2007 to determine its effectiveness in inhibiting the growth of the fungi. It was also carried out to identify the different active constituents present in the Siamese Rough Bush (streblush asper) bark extract through the different phytochemical screenings, the fungicidal or fungistatic of the extract, and if it causes skin irritations when applied to the test animals. The study made use of experimental design. Siamese Rough Bush (streblush asper) bark extract was obtained through maceration and reflux method. The barl extract was prepared into four concentrations-25%, 50%, 75% and 100%. The results are statistically analysed using Analysis of Variance (ANOVA) and Least Significant Difference (LSD). Results of the study showed that the Siamese Rough Bush (Streblush asper) bark extract contain constituents such as saponin glycosides, tannins, proteins, and flavonoids. Based on the statistical analysis, results showed that 75% and 100% concentration have no significant difference with Tolnaftate (Tinactin) with regard to antifungal activity. Based on the test on its inhibitory response, the 100% concentration of Siamese Rough Bush (streblush asper) bark extract show a positive result on its fungistatic action. Siamese Rough Bush (streblush asper) bark extract did not produce any skin irritation on the treated guinea pigs ; therefore, it is safe for application in the skin


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