TY  - BOOK
AU  - Acio, Divine Grace A. [and three others]
TI  - Wound healing property of Kangkong (Ipomoae aquatica) leaf and stem ointments on guinea pigs (Cavia porcellus) 
PY  - 2008///
N1  - Thesis (Bachelor of Science in Pharmacy) -- Mariano Marcos State University - College of Health Sciences, Batac City; Bibliography:  leaves 44-45
N2  - ABSTRACT; ACIO, DIVINE GRACE A., CALLITONG, JAMES V., IFURUNG, ALLAIN MAREN P., LIM, APRIL MAE U.  .  Undergraduate Thesis.  Mariano Marcos State University, College of Health Sciences, Department of Pharmacy, City of Batac. October 2008. WOUND HEALING PROPERTY OF KANGKONG (Ipomoea Aquatica) LEAF AND STEM OINTMENT ON GUINEA PIGS (Cavia porcellus)
 Adviser: Mr. Augustus Ceasar C. Pati
This study identified the active constituents present in Kangkong (Ipomoea Aquatica) Leaf and Stem Extracts. It also tested the safety and efficacy of Kangkong Leaf and Stem Ointments on wounds. Through its preliminary screening, it was found out that active constituents present in the Kangkong Leaf and Stem Extract were alkaloid, fixed and volatile oil, steroid and tannin. The wound healing property of Kangkong was tested with twenty wound-induced guinea pig. The guinea pigs were subjected to the following treatments: Kangkong Leaf Ointment treatment group;  Kangkong Stem Ointment treatment group; Calmoseptine treatment group; ointment base treatment group; and control group. The test animals were randomly assigned to the treatment group. To determine the possible irritation caused by the Kangkong Leaf Ointment and Stem Ointments, patch test was performed. The healing rate of the five treatment groups was compared. Also the tensile strength of the induced wounds was tested to determine wound healing completeness. The significant differences of the wound reduction rate of the different treatment groups were determined using the F-test Analysis of Variance (ANOVA). In the patch test, the Kangkong Leaf and Stem Ointments showed no visible signs of irritation. Result show that the  Kangkong Leaf and Stem Ointments, and Calmoseptine have no significant difference in healing rate and that the ointment base did not interfere in the healing process. The wound did not open upon the application of 2.94-N force. It was observed that the Kangkong (Ipomoea Aquatica) Leaf and Stem Ointments is an effective as the standard commercially prepared drug, Calmoseptine; thus, Kangkong can be used as an alternative.

ER  -