000			01926nam a22001817a 4500
003			OSt
005			20211026101812.0
008			171019b xxu||||| |||| 00| 0 eng d
040			_aMMSU _cULS
100			_965 _aForonda, Eva Joy A. [and six others]
245			_aFruiting spikes of Cogon (Imperata cylindrica) as a sedative-hypnotic agent _cEva Joy A. Foronda, Jobelyn M. Gonzales, Wilma Lynne T. Padron, Debbie Ann P. Radona, Michelle A. Ruiz, Eva N. Soliven and Jaqueline R. Valdez
260			_c2002
300			_ax, 64 leaves _c28 cm.
500			_aThesis (Bachelor of Science in Pharmacy) -- Mariano Marcos State University - College of Health Sciences, Batac City
504			_aBibliography: leaf 41
520			_aABSTRACT _bThis study determine the potential of cogon fruiting spikes as a sedative-hypnotic agent. It tried to determine if the extract of the fruiting spikes is capable of causing sedation and hypnosis. It also identified the dose needed to sedate the test animals as well as to produce hypnosis. Also, observation on the onset of action of the plant extract when administered to Swiss mice was known and the effect of the extract on the normal sleep pattern was verified. The experimental research design was employed to gather data for the study. The active constituent present in the fruiting spikes of cogon extract was an alkaloid. The fruiting spikes extract possessed sedative-hypnotic property when administered to Swiss mice as test animals. One (1.0) ml of the boiled extract produced sedation while in doubling the dose, there was already production of sleep. the sedative-hypnotic agent induces sleep pattern was altered. With the use of the cogon fruiting spikes extract, the time of sleep is prolonged and sleeping becomes more frequent. Hypnosis was clearly verified through positive results shown by the Swiss mice upon subjected to different parameters.
942			_2lcc _cTHEDIS
999			_c11750 _d11750