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040 _aMMSU
_cULS
100 _9109
_aAntalan, Judy A. [and five others]
245 _aAntipyretic activity of Mungo (Phaseolus radiatus) seed extract
_cJudy A. Antalan [and five others]
260 _c2004
300 _axii, 47 leaves
_c28 cm.
500 _aThesis (Bachelor of Science in Pharmacy) -- Mariano Marcos State University - College of Health Sciences, Batac City
504 _aBibliography: leaf 25
520 _aABSTRACT
_bABSTRACT Antalan, J.A., Caleja, M.R., Carlos, J.R., EraƱa, B.A. Martinez, M.R., Raralio, J.N..; Mariano Marcos State University, College of Health Sciences, Department of Pharmacy, Batac City 2906 Ilocos Norte, October 2004. ANTIPYRETIC ACTIVITY OF MUNGO (Phaselous Radaitus) SEED EXTRACT THESIS ADVISER: MS. JANELYN P. VIADO This study was conducted to determine the effectiveness of mungo (Phaselous Radaitus) seed extract as antipyretic agent. It also determined the effective dose that produces the highest decrease in body temperature of the fever-induced test animals of the phytochemical substances present in the extract. The reflux method of extraction was employed. Extract was subjected to phytochemical analysis for the presence of alkaloid, saponin glycosides, tannins, anthraquinones, flavonoids, fats, fixed oil, proteins and carbohydrates, cardenolides and bufadionolides. The effectectiveness of the seed as antipyretic agent was tested in 12 fever-induced guinea pigs using the computer dose of 125 mg/kg, 250 mg/kg and 300 mg/kg per body weight. Body temperature was measured after 30 minutes and hourly for 3 consecutive hours. The procedure was done for the 2nd and 3rd administration of the seed extract. The statistical used in the analysis of data was ANOVA. Results revealed that mungo seed extract contains alkaloids, saponin glycosides, tannins, carbohydrates, proteins and fixed oils. Mungo seed extract was capable of exerting its antipyretic effect up to one hour following extract administration and that the lowest dose manifested the greatest effect in decreasing effect in decreasing the body temperature of the fever-induced test animal.
942 _2lcc
_cTHEDIS
999 _c11771
_d11771