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040 _aMMSU
_cULS
100 _9142
_aBinarao, Celian Lilet I. [and three others]
245 _aEfficacy of Siamese rough bush (Streblus asper) bark extract against Trichophyton mentagrophtytes
_cCelian Lilet I. Binarao [and three others]
260 _c2007
300 _ax, 53 leaves
_c28 cm.
500 _aThesis (Bachelor of Science in Pharmacy) -- Mariano Marcos State University - College of Health Sciences, Batac City
504 _aBibliography: leaves 33-35
520 _aABSTRACT
_bABSTRACT Binarao, Celian Lilet L., Co, Kristine G., Pascual, Mary Anne Q., Rabanal, Suzette T. . Undergraduate thesis. Mariano Marcos State University, College of Health Sciences, Department of Pharmacy, Batac City 2906 Ilocos Norte, October 2007. EFFICACY OF SIAMESE ROUGH BUSH (Streblush Asper) BARK EXTRACT AGAINST Trichopython Mentagrophytes 70 pp Thesis Adviser: Ms. Kristian Gay Y. Dutdut The study investigated the efficacy of Siamese Rough Bush (streblush asper) bark extract against Trichopython mentagrophytes. It was conducted from August to September 2007 to determine its effectiveness in inhibiting the growth of the fungi. It was also carried out to identify the different active constituents present in the Siamese Rough Bush (streblush asper) bark extract through the different phytochemical screenings, the fungicidal or fungistatic of the extract, and if it causes skin irritations when applied to the test animals. The study made use of experimental design. Siamese Rough Bush (streblush asper) bark extract was obtained through maceration and reflux method. The barl extract was prepared into four concentrations-25%, 50%, 75% and 100%. The results are statistically analysed using Analysis of Variance (ANOVA) and Least Significant Difference (LSD). Results of the study showed that the Siamese Rough Bush (Streblush asper) bark extract contain constituents such as saponin glycosides, tannins, proteins, and flavonoids. Based on the statistical analysis, results showed that 75% and 100% concentration have no significant difference with Tolnaftate (Tinactin) with regard to antifungal activity. Based on the test on its inhibitory response, the 100% concentration of Siamese Rough Bush (streblush asper) bark extract show a positive result on its fungistatic action. Siamese Rough Bush (streblush asper) bark extract did not produce any skin irritation on the treated guinea pigs ; therefore, it is safe for application in the skin
942 _2lcc
_cTHEDIS
_k49
999 _c11793
_d11793