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040 _aMMSU
_bULS
_cULS
100 _aBinarao, Celian Lilet L., et al.
245 _aEfficacy of Siamese Rough Bush (Streblus asper) bark extract against tricophyton mentagrophytes /
_cCelian Lilet L. Binarao, Kristine G. Co, Mary Anne Q. Pascual and Suzette T. Rabanal
260 _a2007
300 _ax, 53 leaves
_b28 cm.
500 _aThesis (BS in Pharmacy) - Mariano Marcos State University - College of Health Sciences, Batac City
504 _aBibliography : 51 leaves
520 _aABSTRACT
_bBinarao, Celian Lilet L., Co, Kristine G., Pascual, Mary Anne Q., Rabanal, Suzette T. Undergraduate thesis. Mariano Marcos State University, College of Health Sciences, Department of Pharmacy, Batac City. October 2007. EFFICACY OF SIAMESE ROUGH BUSH (Streblush Asper) BARK EXTRACT AGAINST Trichopython Mentagrophytes. 52 pp Adviser: Ms. Kristian Gay Y. Dutdut The study investigated the efficacy of Siamese Rough Bush (Streblush Asper) Bark Extract Against Trichopython Mentagrophytes. It was conducted from August to September 2007 to determine its effectiveness in inhibiting the growth of the fungi. It was also carried out to identify active constituents present in the Siamese Rough Bush (Streblush Asper) Bark Extract through the different phytochemical screenings, the fungicidal or fungistatic effect of the extract, and if it causes skin irritations when applied to the test animals. The study made use of experimental design. Siamese Rough Bush (Streblush Asper) Bark Extract was obtained through maceration and reflux method. The bark extract was prepared into four concentrations-25%, 50%, 75% and 100%. The results are statistically analysed using Analysis of Variance (ANOVA) and Least Significant Difference (LSD). Results of the study showed that the Siamese Rough Bush (Streblush Asper) Bark Extract contain constituents such as saponin glycosides, tannins, protein, and flavonoids. Based on the statistical analysis, results showed that 75% and 100% concentration have no significant difference with Tolnaftate (Tinactin) with regard to antigungal acvtivity. The Siamese Rough Bush (Streblush Asper) Bark Extract did not produce any skin irritation on the treated guinea pigs; therefore, it is safe for application in the skin.
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_cBK
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_d16545