000 02559nam a22001817a 4500
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040 _aMMSU
_bULS
_cULS
100 _aFlorina, Charlene D., et al.
245 _aExtraction of Active Constituents from the Fresh Leaves of Jatropha Curcas, Linn (Tubang-Bakod) as an Antifungal Agents
_cCharlene D. Florina, Winiemar Loverlyn V. Lorenzo, Ailene Flor S. Orteza, Leilany O. Osavo, Ernelyn A. Pagtama and Glory Ann C. Paguibitan
260 _c2001
300 _avi, 62 leaves.
_b28 cm.
500 _aThesis (Bachelor of Science in Pharmacy) -- Mariano Marcos State University - College of Health Sciences, Batac City
504 _aBibliography: leaves 36
520 _aABSTRACT
_bFLORINA, CHARLENE D., LORENZO, WINIEMAR LOVERLYN V., ORTEZA, AILENE FLOR S., OSALVO, LEILANY O., PAGTAMA, ERNELYN A., PAGUIBITAN, GLORY ANN C. : MARIANO MARCOS STATE UNIVERSITY, COLLEGE OF HEALTH SCIENCES, DEPARTMENT OF PHARMACY, BATAC CITY 2906 ILOCOS NORTE, OCTOBER 2001. EXTRACTION OF ACTIVE CONSTITUENTS FROM THE FRESH LEAVES OF JATROPHA CURCAS, LINN (TUBANG BAKOD) AS AN ANTIFUNGAL AGENTS. THESIS ADVISER: MRS. GEMMA C. VINLUAN This study investigated the fungicidal property of Jatropha curcas against the three microbes such as tinea capitis, tinea corporis, and tinea pedis. The most effective against the microbes and the minimum inhibition concentration to inhibit the growth were determined. All of the experimental set-up was compared with the standard drug Miconazole. The pre-experimental research desin was employed in the study to determine the effect of of Jatropha curcasleaves extract against the three fungi. The active constituents of of Jatropha curcas that can inhibit the growth of fungi were the alkaloids, tannins, saponon glycosides, and resins. Likewise, fatty acids essentials for the formulation of drugs were also present in the leaves extract. The standard drug was the most effective against tinea capitis, tinea corporis, and tinea pedis as compared to any of the concentration of the of Jatropha curcas leaves extract. Moreover, the 100% concentration of the leaves extract was the most effective agent against tinea pedis. Both tine capitis and tines corporis were greatly inhibited by the 75% concentration. All the different concentrations used in this study together with the standard drug showed antifungal property. The study revealed that the minimum concentration that can inhibit the growth of fungi was the 25%.
942 _2lcc
_cTHEDIS
999 _c16723
_d16723