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040 _aMMSU
_bULS
_cULS
100 _aDescalzo, Eymard Caesar Y., Pagdilao, Eizen Queene L., Simeon, Ellaine A.
245 _aHypoglycemic Activity Of The Crude Extract Of Tampoi (Syzigium Jambos Linn. ) Leaves On Alloxan-Induced Hyperglycemia In Albino Rats /
_cEymard Ceasar Y. Descalzo, Eizen Queene L. Pagdilao., Ellaine A. Simeon
260 _c2015
300 _axi, 82 leaves
_b28 cm.
500 _aThesis (Bachelor of Science in Pharmacy) -- Mariano Marcos State University - College of Health Sciences, Batac City
504 _aBibliography: leaves 41-43
520 _aABSTRACT
_bDESCALZO, ECY., PAGDILAO, EQL., SIMEON, ES., U Mariano Marcos State University, College of Health Sciences, Department of Pharmacy, City of Batac 2906, Ilocos Norte. March 2015. Hypoglycemic Activity Of The Crude Extract Of Tampoi (Syzigium Jambos Linn. ) Leaves On Alloxan-Induced Hyperglycemia In Albino Rats. Adviser: Kristian Gay Y. Dutdut Diabetes mellitus is ranked 8th among the leading causes of mortality in the Philippines. Many plant treatments for diabetes have been recorded, but only a small number of these have received assessment for their efficacy. This study used a randomized pre test – post tets experimental research design to determine the hypoglycemic activity of the crude extract of Tampai leaves (CETL) on Alloxan induced hyperglycemia in Albino rats. The powdered plant material was macerated for 48 hours and the extract was obtained by rotary evaporation. Phytochemical screening was conducted to determined the constituents present in CETL. Fifteen Albino rats were utilized and divided into five groups. Group I served as the Normal Control while the other groups were injected with Alloxan to become hyperglycemic and as follows: Group II (Hyperglycemic Control given with PNSS 20mL/Kg), Group III (Positive Control treated with Glibenclamide 6.75 mg/Kg), Group IV (CETL 500 mg/kg) and Group V (CETL 500 mg/kg). it was found out that CETL contains hydrolysable tannins, saponins, fixed oils, proteins and anthraquinones. Pharmacological assay revealed that CETL 250 mg/kg and CETL 500 mg/kg are comparable with Glibenclamide and are all effective as hypoglycemic agents by means of lowering FBS, increasing weight and normalizing serum lipid levels.
942 _2lcc
_cTHEDIS
999 _c17145
_d17145