000			02282nam a22001817a 4500
003			OSt
005			20220511105238.0
008			220511b |||||||| |||| 00| 0 eng d
040			_aMMSU _bULS _cULS
100			_aBaga, Erika Camille R., Bajo, Nely Rose B., Matias, Reganne Ray G.
245			_aAnti-diabetic activity of Kamias (Averrhoa bilimbi Ox.) fruit extract on alloxan-induced diabetic rats / _cErika Camille R. Baga., Nely Rose B. Bajo., Reganne Ray G. Matias
260			_c2014
300			_axiii, _b82 leaves, _c28 cm.
500			_aThesis (Bachelor of Science in Pharmacy) -- Mariano Marcos State University - College of Health Sciences, Batac City
504			_aBibliography: leaves 41-42
520			_aABSTRACT _bBAGA ECR, BAJO NRB, MATIAS RRG. Anti-diabetic activity of kamias (Averrhoa bilimbi Ox.) fruit extract in alloxan-induced diabetic rats. Mariano Marcos State University. March 2014. Adviser: Ms. Ma. Danica I. Ramil The present study aimed to evaluate the anti-diabetic activity of kamias (Averrhoa bilimbi Ox.) fruit extract in alloxan-induced diabetic rats. The pure extract was obtained by defatting the freeze-dried kamias (Averrhoa bilimbi) fruit with petroleum ether, extraction through maceration with 95% ethanol and rotary evaporation at 40°C. one-way analysis of variance and least significant difference test were employed in the statistical analysis of data. The phytochemical screening revealed the presence of tannins and saponins in Kamias fruit extract. In the Brine Shrimp Lethality Bioassay, the Kamias fruit extract is found to be practically non-toxic with an LC50 value of 123284.6739 mcg/ml. In pharmacological testing, alloxan-induced diabetic rat-groups untreated and treated with Glibenclamide and Kamias fruit extract and non-diabetic rat –group were evaluated for 21 days. Blood glucose level, body weight, feed and liquid intake, urine output and urinary glucose level was use as parameters. The results revealed that the anti-diabetic activity of Kamias fruit extract were comparable with Glibenclamide in terms of lowering blood glucose level, increasing body weight, decreasing feed and liquid intake, urinary glucose level (p<0.01) and urine output (p<0.05) after 21 days.
942			_2lcc _cTHEDIS
999			_c17259 _d17259