Hepatoprotective effect of screw pine (Pandanus adoratissimus) leaf extract in paracetamol-induced liver injury in rats / (Record no. 17214)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02353nam a22001817a 4500 |
| 003 - CONTROL NUMBER IDENTIFIER | |
| control field | OSt |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20220404143608.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 220404b |||||||| |||| 00| 0 eng d |
| 040 ## - CATALOGING SOURCE | |
| Original cataloging agency | MMSU |
| Language of cataloging | ULS |
| Transcribing agency | ULS |
| 100 ## - MAIN ENTRY--PERSONAL NAME | |
| Personal name | Castro, Sheryl B., Francisco, Sarah Joy C., Quigao, Glen-John A., |
| 245 ## - TITLE STATEMENT | |
| Title | Hepatoprotective effect of screw pine (Pandanus adoratissimus) leaf extract in paracetamol-induced liver injury in rats / |
| Statement of responsibility, etc. | Sheryl B. Castro., Sarah Joy C. Francisco., Glen-John A. Quigao, |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. | |
| Date of publication, distribution, etc. | 2014 |
| 300 ## - PHYSICAL DESCRIPTION | |
| Extent | viii, 72 leaves |
| Other physical details | 28 CM. |
| 500 ## - GENERAL NOTE | |
| General note | Thesis (Bachelor of Science in Pharmacy) -- Mariano Marcos State University - College of Health Sciences, Batac City |
| 504 ## - BIBLIOGRAPHY, ETC. NOTE | |
| Bibliography, etc. note | Bibliography: 36 – 37 leaves |
| 520 ## - SUMMARY, ETC. | |
| Summary, etc. | ABSTRACT |
| Expansion of summary note | Castro, SB., Francisco, SJC., Quigao, GA., Mariano Marcos State University, College of Health Sciences, Department of Pharmacy, 2906 City of Batac, March 2014. Hepatoprotective effect of screw pine (Pandanus adoratissimus) leaf extract in paracetamol-induced liver injury in rats<br/>Adviser: Ms. Angelica May A. dela Cruz<br/><br/>The reserachers tested the potential property of of screw pine (Pandanus adoratissimus) as a hepatoprotective agent against paracetamol induced hepatotoxicity using pre-test-posttest research design. Confirmatory phytochemical screening using the method of Kusuma et. al. (2012), showed that the leaf extract contains flavonoids, saponin and tannins which maybe responsible for its hepatoprotective activity. Oral acute toxicity test was performed using the Organisation for Economic Coopertaion and Development (OECD) guideline. Observation was done for a total of 14 days were none of the dosed test animals died which means that the leaf extract is safe and nontoxic. <br/>The rats treated with 1000 mg of Screw Pine leaf extract was comparable with that of 100 mg of Silymarin in terms of blood ALT and AST enzyme. Histopathological screening also revealed that Screw Pine leaf extract at 1000 mg/kg dose is comparable with that of the positive control treated with Silymarin at 100 mg/kg dose in terms of their histhopathological features. The data gathered were statistically analyzed using ANOVA. based on the results of the study there is no significant difference in the Hepatoprotective property between Silymarin and the Screw Pine leaf extract<br/><br/> |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Source of classification or shelving scheme | |
| Koha item type | Thesis/Dissertation |
| Withdrawn status | Lost status | Source of classification or shelving scheme | Damaged status | Not for loan | Home library | Current library | Date acquired | Barcode | Date last seen | Price effective from | Koha item type |
|---|---|---|---|---|---|---|---|---|---|---|---|
| MMSU College of Health Sciences | MMSU College of Health Sciences | 04/04/2022 | 206-Pharm | 04/04/2022 | 04/04/2022 | Thesis/Dissertation |